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Pharmacology of licorice




It is used for palpitations due to lack of heart-qi, intermittent pulse, fatigue and fatigue due to weak temper, lack of food and loose stools. Can benefit the Qi of the heart and spleen. To treat heart-qi deficiency, it is often used as the main ingredient, and it is used in combination with ginseng, donkey-hide gelatin, and cassia twig, such as Zhigancao Decoction. To treat spleen deficiency, it is often used with Codonopsis pilosula and Atractylodes macrocephala.

For cough with phlegm. It can eliminate phlegm and relieve cough, and can be widely used in suitable combination with the disease. For wind-cold cough, it can be combined with ephedra and almonds; for lung-heat cough and asthma, it can be combined with gypsum, ephedra, almonds, for cough and asthma with cold phlegm, with dried ginger and asarum, for cough with damp phlegm, pinellia, and Poria.

For epigastric and extremity spasms acute pain. Can relieve pain. If it is caused by deficiency of yin and blood, tendons lose their nourishment and convulsions, acute pain, often take white peony root, that is, Shaoyao Gancao Decoction; Medium soup. In recent years, it has been reported that licorice powder alone or in combination with cuttlefish bone and corrugated seeds has good short-term curative effect in the treatment of gastric and duodenal ulcers.

Used in prescriptions with strong medicinal properties. It can alleviate the strong or reduce the toxic and side effects, and it can also reconcile the spleen and stomach. For example, Tiaowei Chengqi Decoction uses licorice to alleviate the nature of nitrate and yellow, so that the diarrhea will not be too violent, and to avoid abdominal pain caused by its stimulation of the large intestine. It can be used to harmonize cold and heat, level up and down, and play a harmonious role.

It is used for toxic heat sores, sore throat, medicine, food poisoning, etc. Can clear away heat and detoxify. It is often used in conjunction with honeysuckle and forsythia to treat heat-toxin sores. To treat sore throat, it is often used together with Platycodon grandiflorum. To treat drug and food poisoning, when there is no special antidote, licorice can be used to treat it, or it can be taken with mung bean or soybean decoction.




"Materia Medica Zheng" "(Glycyrrhizae) has the effect of neutralizing and tonifying, so the poisonous medicine can be used to detoxify, the hard medicine can be used to harmonize its nature, the superficial medicine can be used to help it, and the medicine can be used to slow down its speed." Enter the Qi with the qi medicine, enter the blood with the blood medicine, there is no way to go, so it is called the old man, but do not add it to those who are moderately full, for fear that it will cause swelling; do not enter it if it is slow, for fear that it will slow down the work, you must not know it. "




Decoction, 3~10g. It should be used raw for clearing heat and detoxifying, and it should be used for broiling for nourishing the middle-Jiao.


Note taboo


It is not suitable for people with dampness, fullness and swelling. Anti-euphorbia, genkwa, kansui, seaweed. Taking large doses of raw licorice for a long time can cause edema and so on.


Modern Pharmacology


Licorice roots and rhizomes contain glycyrrhizin, which is the diglucuronide of glycyrrhetinic acid, the sweet component of licorice. In addition, it still contains a variety of flavonoids.


Licorice has a similar effect to adrenal cortex hormones. It can inhibit the hypersecretion of gastric acid caused by histamine; it also has the effect of antacid and relieving spasm of gastrointestinal smooth muscle.

Licorice flavonoids, licorice extract and glycyrrhetinic acid all have obvious antitussive effect, and expectorant effect is also more significant, and the action intensity is glycyrrhetinic acid > licorice flavonoids > licorice extract.

Licorice also has anti-inflammatory and anti-allergic effects, and can protect the mucous membranes of the inflamed throat and trachea.

Licorice extract and glycyrrhizin have detoxification effects similar to glucuronic acid on certain poisons.

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