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2022-08-25

The accumulation rule of secondary metabolites in Astragalus root from different origins was discussed, and the accumulation and diameter of secondary metabolites in Astragalus root were described. (4) To clarify the accumulation rule of secondary metabolites in different parts of Astragalus, to reveal the scientificity of traditional "diagnosis and quality differentiation" of Astragalus, and to provide a theoretical basis for the rational utilization of Astragalus. Astragalus Resource Basis. Methods: (1) Combined with the methods of origin investigation and market investigation, the cultivation history, cultivation environment, cultivation methods, processing methods, and commodity specifications of the main cultivation areas of Astragalus in my country were studied. Shanxi, Inner Mongolia, Gansu d other places were analyzed. Field investigation and research were carried out; (2) The quality evaluation of Athe astragalus root in the past dynasties was reviewed and summarized; (3) based on the early developmental anatomy of astragalus root, the HPLC-DAD method was used to determine the four isoflavone glycosides, awn The content of isoflavones and formononetin in the flower of the flower, revealing the diameter of astragalus and the distribution and accumulation of isoflavones; (< @4) Determination of four isoflavones in the hollow and non-hollow parts of Astragalus in Shanxi Hunyuan,

Gansu and Inner Mongolia Astragalus 2-3 years after transplanting, the main root is about 15-30 cm long, and the diameter near the root head is less than 15-30 cm. @0.8-1.8cm or so, the texture of Astragalus is slightly hard Astragalus root, the main root of Hunyuan Astragalus in Mongolia is more than 30 cm, the diameter near the root is mostly < @1.2cm-3.5cm, the texture is soft, and the xylem near the root has a hollow phenomenon; The processing method of Mongolian Astragalus varies from place to place. Currently, most of it is processed by pharmaceutical companies and drug dealers. After processing, Mongolian Astragalus from Gansu and Inner Mongolia can be divided into horizontal slices, oblique slices, and oblique slices after being flattened. There are many kinds of decoction pieces prepared from Astragalus, and most of the product specifications of Astragalus are unified, and there is no unified specification; Shanxi Hunyuan Mongolian Astragalus follows the traditional processing method. Exquisite processing technology. The processed astragalus is divided into different commodity specifications and grades according to diameter, length, and processing method. The processing of decoction pieces mainly includes melon seeds and Zhengbei pieces; the recorded germplasm sources are the same; the Dao production areas of astragalus in the past dynasties have changed from time to time with the different dynasties. The Southern and Northern Dynasties used to be dominated by Gansu, the Tang Dynasty was dominated by Shaanxi, and the Song Dynasty was dominated by Shanxi. It is closely related to the place of origin, "distinguishing quality", processing methods, etc.; and the "identifying quality" of Astragalus is related to its color, taste, texture, shape, etc.; (3) Gansu, Inner Mongolia seedling transplanting 2-3 2009 Astragalus The root system is hard, while Shanxi Hunyuan Astragalus is softer, and the contents of four isoflavones in the roots are different in Daoji area. The sum of the isoflavones is the highest, and the diameter is greater than 2. The sum of the four isoflavones is higher at 2cm, and the diameter is between 1.0-2.2cm. The sum of the four isoflavones fluctuates within a certain range with the diameter. Shanxi Hunyuan The ratio of four isoflavones in Astragalus root is different from Gansu and Inner Mongolia. In Astragalus roots with different diameters, the sum of the contents of formononetin and formononetin was greater than 5, and the ratio of the sum of the contents of glucosinolate and formononetin to the sum of the contents of verbenone and formononetin was greater than 5. Inner Mongolia and Gansu were less than 1; (4) The contents of four isoflavones in different parts of Astragalus in the Hunyuan and Daoji areas of Shanxi were different, and the contents of four isoflavones in the hollow and non-hollow parts of the roots were different. The contents of four isoflavones in the hollow part Sometimes it was lower than the non-hollow part and other parts, sometimes higher than the non-hollow part and other parts; the contents of the four isoflavones in the upper, middle, lower, and lower lateral roots of the non-hollow part of Astragalus root with different diameters were also different.

Conclusion: (1) Gansu, Inner Mongolia, and Shanxi are still the main producing areas of Astragalus; the quality and clinical efficacy of Astragalus seedlings transplanted in Gansu and Inner Mongolia after 2-3 years still need further research; the processing methods of Astragalus are rich and varied, and the processing methodld be increased. In-depth research on the specifications of Astragalus and decoction pieces; the texture of Mongolian Astragalus produced in Gansu, Inner Mongolia, and Shanxi is quite different; (2) There are many Astragalus germplasm resources recorded in Materia Medica, but the source of authentic Astragalus is relatively simple; production area and "distinguishing quality"; the current commercial specification of Astragalus is the continuation of the quality evaluation of the medicinal material Astragalus in past dynasties; (3) In different production areas, the proportions of the four isoflavones in Astragalus Mongolia are different, and the proportions of these four isoflavones are different It may be one of the main features that distinguish Astragalus from Shanxi Hunyuan in Daoji area and non-Daoji area. In crude roots, the sum of the four isoflavones fluctuates within a certain range under different diameters; (4) The contents of four isoflavones in different parts of Astragalus vary greatly; the contents of four isoflavones in the hollow and non-hollow parts Different, the generation of the hollow part has a certain influence on the content of the four isoflavones in the root. Combined with the traditional quality evaluation and the current processing method, it is recommended to use the hollow part of the root of astragalus rationally.

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